Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study (post)

Pharos University in Alexandria

Status and phase: Enrolling; Phase 3; Phase 2

Conditions: Postoperative Sore Throat

Treatments: Drug: Topical dexamethasone; Drug: 10% lidocaine was sprayed over the tube for the second group

Study type: Interventional

Funder types: Other

Identifiers

NCT06266481

pua04202312313157

Details and patient eligibility

About

postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted.

Full description

postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted.In this study, 100 patients were intubated to undergo general anaesthesia for shoulder arthroscopy and randomised into one of two groups. An endotracheal tube was soaked in 8mg of dexamethasone for the first group intubation, while 10% lidocaine was sprayed over the tube for the second group. Following extubation, the two groups examined the severity of sore throats

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• •Patients belonging to ASA physical status I, II

  • Patients between age18 to 50 years
  • Patients belonging to both genders.
  • patients undergoing shoulder arthroscopic surgeries.
  • Patients with fasting blood glucose <100 mg/dl or random blood sugar <140 mg/dl.

Exclusion criteria

• Patients who are not willing to give consent for participation in the study

  • Patients with anticipated difficult airway
  • Patients who are allergic to steroids.
  • Patients with ASA physical status III, IV
  • Diabetic patients.
  • Patients on steroids
  • Patients requiring nasogastric tube or throat pack.
  • Patients posted for head and neck surgeries.
  • patient with GERD
  • Pregnant patients
  • preexisting upper respiratory tract infection.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

dexamethasone group

Active Comparator group

Description:

An endotracheal tube was soaked in 8mg of dexamethasone for group I intubation

Treatment:

Drug: Topical dexamethasone

lidocaine group

Active Comparator group

Description:

10% lidocaine was sprayed over the tube

Treatment:

Drug: 10% lidocaine was sprayed over the tube for the second group