Topical Ice-therapy for Intravitreal Injections

University of Minnesota (UMN)

Status: Completed

Conditions: Injection Site Irritation; Anesthesia; Hypothermia

Treatments: Other: Ice-therapy; Other: No Ice-therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05269823

OPH-2022-30605

Details and patient eligibility

About

Purpose: To examine the difference in patient's pain experience in the setting of intravitreal anti-VEGF injections with pretreatment of topical ice-therapy compared with no-ice.

Enrollment: 42 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• All patients aged 18 or older evaluated by a single retina specialist at the University of Minnesota Department of Ophthalmology with a clinical indication necessitating an anti-VEGF intravitreal injection

Exclusion criteria

• N/A

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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42 participants in 2 patient groups, including a placebo group

Ice-therapy

Active Comparator group

Description:

Ice therapy will be provided prior to the provision of the intravitreal injection

Treatment:

Other: Ice-therapy

No Ice-therapy

Placebo Comparator group

Description:

No ice therapy will be provided prior to the provision of the intravitreal injection

Treatment:

Other: No Ice-therapy