Topical Lidocaine for Needle Insertion and Injection Pain

New York School of Regional Anesthesia

Status

Completed

Conditions

Needle Insertion and Injection Pain

Treatments

Drug: Lidocaine Topical

Study type

Interventional

Funder types

Other

Identifiers

NCT03206320

SMBe1701

Details and patient eligibility

About

Skin infiltration with local anesthetic is commonly used to decrease patient discomfort during peripheral nerve blocks. Topically applied local anesthetic gel might provide analgesia while eliminating the need for additional injections. The primary objective of this study was a noninferiority comparison between the analgesia achieved with topical gel with that of skin infiltration for pain upon needle insertion and injection during administration of the interscalene brachial (ISBP) and axillary (AX) plexus blocks.

Enrollment

30 patients

Sex

All

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Ability to understand Dutch, French or English language, purpose and risks of the study, provide signed and dated informed consent and authorization to use protected health information (PHI) in accordance with national and local subject privacy regulations
Age >18 at the time of informed consent
ASA I-III physical class
Scheduled for elective shoulder or upper arm surgery requiring a preoperative interscalene brachial (ISBP) or axillary (AX) plexus block

Exclusion criteria

History of an allergy or contra-indication to a local anesthetic
Baseline neurological deficit
Medical condition that will make it difficult to assess sensory distribution or communicate with a staff member
Presence of preexisting coagulation disorders
Infection at injection site
Concomitant opioid therapy
Recent history (<3 months) of drug or alcohol abuse
Female subjects who are pregnant or currently breastfeeding, or who have a positive pregnancy test result at first visit