Topical Oral Anesthesia Adjuncts in Conventional Intubation on First-Pass Success Rate

Queen Savang Vadhana Memorial Hospital, Thailand

Status: Enrolling

Conditions: Unrecognized Condition

Treatments: Drug: Lidocaine spray

Study type: Interventional

Funder types: Other

Identifiers

NCT06661967

017/2567

Details and patient eligibility

About

This study aims to determine the first-pass success rate in video laryngoscopy and other parameters that topical anesthesia can affect during intubation.

Full description

In Thailand, conventional intubation or sedation without paralysis is still the most common method of intubation due to the lack of emergency physicians at primary care centers. A pilot study had shown that topical oral anesthesia can improve the first-pass success rate in conventional intubation by direct laryngoscopy. This study aims to determine the first-pass success rate in video laryngoscopy and other parameters that topical anesthesia can affect during intubation.

Enrollment: 110 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients in emergency department that have indication for conventional intubation
• Age > 18 yr

Exclusion criteria

• Patient who undergo RSI
• Patient who falls in cardiac arrest airway algorithm
• Patient who is currently pregnancy
• Known allergy to lidocaine

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

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110 participants in 2 patient groups, including a placebo group

Lidocaine spray

Active Comparator group

Description:

Spray lidocaine 10 puffs at oropharynx during preoxygenation if the patient body weight is lower than 60kg, otherwise 15 puffs

Treatment:

Drug: Lidocaine spray

Placebo

Placebo Comparator group

Description:

Spray normal saline 10 puffs at oropharynx during preoxygenation if the patient body weight is lower than 60kg, otherwise 15 puffs

Treatment:

Drug: Lidocaine spray