Topical PDT Cream Without Irradiation Source in the Acne Treatment

Seoul National University

Status: Completed

Conditions: Acne, Photodynamic Therapy

Treatments: Drug: Topical application of sham control; Drug: Topical application of 1.5% Butenyl ALA

Study type: Interventional

Funder types: Other

Identifiers

NCT02313467

SNUH-PDT2

Details and patient eligibility

About

In this study, the investigators are going to compare the clinical effect and safety of topical application of 1.5% Butenyl ALA cream formula without light source irradiation in the treatment of acne.

Enrollment: 45 patients

Sex: All

Ages: 19 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• mild to moderate acne vulgaris (Leeds revised acne grading system score 2-7) at baseline.

Exclusion criteria

• known pregnancy
• lactation
• any medical illness that might influence the results of the study
• a history of oral acne medication or surgical procedure, including laser treatment, within 6 months of study enrollment
• use of topical acne medication within 4 weeks of study enrollment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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45 participants in 2 patient groups

1.5% Butenyl ALA

Active Comparator group

Description:

Topical application of 1.5% Butenyl ALA per every other day around acne lesions in the face

Treatment:

Drug: Topical application of 1.5% Butenyl ALA

Control

Sham Comparator group

Description:

Topical application of sham control per every other day around acne lesions in the face

Treatment:

Drug: Topical application of sham control