Topical Phytoterpenes for Plantar Fasciitis

Population Counci

Status: Completed

Conditions: Plantar Fasciitis

Treatments: Other: Topical oil application

Study type: Interventional

Funder types: Industry

Identifiers

NCT05467631

PF-001

Details and patient eligibility

About

Randomized controlled trial of mixture of essential oils containing tea tree oil, rosemary, clove, pepper, in a formulation with skin permeation enhancers including limonene for the treatment of plantar fasciitis in adult men and women. Forty-two patients will be randomized to receive twice daily topical application of the treatment formulation or plain tea tree oil as a control. Analog pain scores will be assessed at the start of treatment and at two weeks. Analysis will be by student's T-test.

Full description

Randomized controlled trial of mixture of essential oils containing tea tree oil, rosemary, clove, pepper, in a formulation with skin permeation enhancers including limonene for the treatment of plantar fasciitis in adult men and women. Forty-two patients will be randomized to receive twice daily topical application of the treatment formulation or plain tea tree oil as a control. Analog pain scores will be assessed at the start of treatment and at two weeks. Analysis will be by student's T-test. Primary outcome measure will be the difference in pain score between baseline score and pain score at 2 weeks.

Enrollment: 42 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Plantar fasciitis diagnosed by a medical practitioner and at least 3 months in duration

Exclusion criteria

• Age under 18 years, any history of diabetes, history of foot surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

42 participants in 2 patient groups

Plain Tea Tree Oil Control

Active Comparator group

Description:

Topical application of 1ml 20% tea tree oil in almond oil base as a carrier twice daily for 2 weeks.

Treatment:

Other: Topical oil application

Verum

Experimental group

Description:

Topical application twice daily of 1ml mixture for 2 weeks of essential oils containing tea tree oil, rosemary, clove, pepper, in a formulation with skin permeation enhancers including limonene.

Treatment:

Other: Topical oil application