Topical Radial Artery Vasodilation

University of California San Francisco (UCSF)

Status and phase: Completed; Phase 3; Phase 2

Conditions: Cardiac Catheterization; Spasm

Treatments: Drug: Nitroglycerin and lidocaine; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01155167

CHR # 10035824 (Other Identifier)

10035824

Details and patient eligibility

About

The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm. Patients undergoing cardiac catheterization via the radial artery will be randomized to topical nitroglycerin + lidocaine versus placebo.

Full description

The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm. Patients undergoing cardiac catheterization via the radial artery will be randomized to topical nitroglycerin + lidocaine versus placebo.

Enrollment: 86 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Undergoing trans-radial cardiac catheterization

Exclusion criteria

• inability to receive nitroglycerin or lidocaine due to allergy or medication interactions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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86 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Treatment:

Other: Placebo

Topical dilator

Experimental group

Treatment:

Drug: Nitroglycerin and lidocaine