Total Knee Arthroplasty With and Without Tourniquet: Comparative Study

Hawler Medical University

Status: Completed

Conditions: Total Knee Arthroplasty

Treatments: Procedure: Tourniquet use

Study type: Interventional

Funder types: Other

Identifiers

NCT04130009

HMU/Sherwan4

Details and patient eligibility

About

Tourniquet use during total knee arthroplasty (TKA) improves visibility and reduces intraoperative blood loss. However, tourniquet use may also have a negative impact on early recovery of muscle strength and lower extremity function after TKA.Seventy Patients are involved in this study and were divided into two groups; Group A (35) patients were treated with TKA with pneumatic thigh tourniquet. Group B (35) patients were treated with TKA without tourniquet. All patients were suffering from severe knee osteoarthritis and they failed to respond to conservative treatment so they are candidates for primary TKA. The two groups are matched related to age and gender. Selection of patients into two groups done randomly with regard of odd number for group A and even number for group B

Full description

This study started on March 2016 and ends on October 2018. Seventy Patients are involved in this study and were divided into two groups; Group A (35) patients were treated with TKA with pneumatic thigh tourniquet. Group B (35) patients were treated with TKA without tourniquet. All patients were suffering from severe knee osteoarthritis and they failed to respond to conservative treatment so they are candidates for primary TKA. The two groups are matched related to age and gender. Selection of patients into two groups done randomly with regard of odd number for group A and even number for group B. All patients were followed for a period of two weeks until removal of skin sutures for the following parameters:

Amount of blood transfusion done at and after surgery. Amount of blood drained postoperatively through suction drain. Occurrence of postoperative wound hematoma. VAS (Visual analogue score) for thigh pain at 1st day and (2) weeks postoperatively.

Clinical DVT.

Enrollment: 70 patients

Sex: All

Ages: 48 to 82 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients were suffering from severe knee osteoarthritis and they failed to respond to conservative treatment

Exclusion criteria

• Hb less than 12.
• D.M.,Blood dyscrasia.
• Any evidence of infection by screening test ESR and CRP. ,
• BMI more than 30.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

TKA with tourniquet

Active Comparator group

Description:

This group was treated by TKA with the use of tourniquet

Treatment:

Procedure: Tourniquet use

TKA without tourniquet

Active Comparator group

Description:

This group was treated by TKA without tourniquet

Treatment:

Procedure: Tourniquet use