Total Laparoscopic Versus Open Aortic Surgery for Abdominal Aortic Disease

University of Poitiers

Status

Completed

Conditions

Graft Occlusion, Vascular

Treatments

Procedure: Aortic repair

Study type

Observational

Funder types

Other

Identifiers

NCT02325700

JBR02

Details and patient eligibility

About

This prospective study was designed to analyse the postoperative and long-term outcomes of total laparoscopic vs. open surgical repair of infra-renal abdominal aortic occlusive disease (AOD) and infra-renal aortic aneurysmal disease (AAA) in comparable groups of patients using a propensity analysis model.

Full description

From January 2006 to January 2010, 228 consecutive patients who received an aortic bypass for AAA (n=139) or for AOD (n=89) were studied. Open repair was performed in145 patients (AAA=109, AOD=36) and total laparoscopic repair in 83 patients (AAA=30, AOD=53). One-to-one propensity score matching between study groups was done according to a difference in the logit of propensity score of less than 0.04 between each patient pairs in the study groups. Logistic regression with the help of backward selection was used to adjust the effect of treatment method for propensity score as well as other variables in evaluating postoperative and long-term outcome. A p value < .05 was considered statistically significant.

Enrollment

228 patients

Sex

All

Ages

30 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Aortic occlusive disease (TASC C & D)
Aortic abdominal aneurysm with a diameter > 5 cm

Exclusion criteria

Patients with an occlusive disease amenable to stenting (TASC A & B)
Patients with an abdominal aortic aneurysm with an anatomy allowing the use of a stent graft (EVAR)
Patients with a life expectancy < 3 years or ASA 4 with a high operative risk