Total Splenectomy vs Partial Splenectomy in Non-malignant Hemoglobinopathies : Study Comparing the Effectiveness

University Hospital Center (CHU)

Status: Unknown

Conditions: Splenectomy; Status

Study type: Observational

Funder types: Other

Identifiers

NCT05184647

RECHMPL21_0712

Details and patient eligibility

About

Partial splenectomy or total splenectomy are the two surgical treatment of non-malignant hemoglobinoptahie. The aim of this treatment is to decrease transfusion. The main risk is infectious in total splenectomy, that's why partial splenectomy was suggest. But the efficiency of partial splenectomy decrease over time and a totalisation could be mandatory.

Enrollment: 100 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children between 0- 18 years olds
• Total or partial splenectomy
• Non malignant hémoglobinopathies

Exclusion criteria

• Total or partial splenectomy outside of non malignant hemoglobinopathies

Trial design

100 participants in 2 patient groups

Children under 18 years olds with total splenectomy for non Malignant hemoglobinopathie

Description:

Children under 18 years olds with total splenectomy for non Malignant hemoglobinopathie

Children under 18 years olds with partial splenectomy for non Malignant hemoglobinopathie

Description:

Children under 18 years olds with partial splenectomy for non Malignant hemoglobinopathie