TOTEM: Trial of TAP Block Effective Medications

Western Michigan University School of Medicine

Status: Unknown

Conditions: Pain, Postoperative

Treatments: Procedure: Transversus abdominis plane (TAP) block with liposomal bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04382859

WMed-2020-0601

Details and patient eligibility

About

Our goal is to determine if liposomal bupivacaine compared to standard bupivacaine results in increased pain control and decreased narcotic pain medication use when used in TAP blocks prior to laparoscopic hysterectomies for benign indications.

Enrollment: 56 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women undergoing non robotic assisted laparoscopic surgery for benign gynecologic conditions
• English speaking

Exclusion criteria

• Known current malignancy
• Contraindication to medications

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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56 participants in 2 patient groups

TAP block with liposomal bupivacaine

Active Comparator group

Description:

Active comparator

Treatment:

Procedure: Transversus abdominis plane (TAP) block with liposomal bupivacaine

TAP block with 0.25% bupivacaine

Other group

Description:

Standard comparator

Treatment:

Procedure: Transversus abdominis plane (TAP) block with liposomal bupivacaine