Tour de Borobudur Troponin Study on Predictors and Synergistic Role of MDA and Hs-CRP Levels (TdBTS)

Universitas Negeri Semarang

Status: Completed

Conditions: Heart Arrest; Inflammatory Response; Sport Injury; Oxidative Stress

Treatments: Other: 140kms cycling

Study type: Observational

Funder types: Other

Identifiers

NCT03310450

0017

Details and patient eligibility

About

Prospective observational study to determine predictors that related to cardiac troponin I (cTnI) release, malondialdehyde (MDA) and high sensitivity C Reactive Protein (hs-CRP) after Tour de Borobudur (TdB) 2017

Full description

Eligible Criteria:

1. minimum sample size of 80 men, non-athlete, participants of TdB
2. Classified into two groups: 160kms cycling and 100kms cycling participation
3. 25-55 years old
4. voluntary participate in the research
5. eligible in pre participatory physical examination and ECG test by the doctor
6. have no history of the previous acute coronary syndrome (ACS)

Measurements:

Interview for determining predictors of sports participation history, medical history, family medical history and Rate of Perceived Exertion Measurement and examination to determine: anthropometry parameters, clinical conditions (Systolic BP, Diastolic BP, hemoglobin levels, T-cholesterol and HDL-C levels, the intensity in cycling activities (mileage, velocity, duration, and time for resting), hemodynamic responses (average and maximum heart rate, Karvonen Index), and Hydration status

Other outcome measurements; pre and post-TdB 2017 measurements of cTnI, MDA, and hs-CRP

Enrollment: 94 patients

Sex: Male

Ages: 25 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• minimum sample size of 80 men, non athlete, participants of TdB
• Classified into two groups: 160kms cycling and 100kms cycling participation
• 25-55 years old
• voluntary participate in the research
• eligible in pre participatory physical examination and ECG test by doctor have no history of previous acute coronary syndrome (ACS)

Exclusion criteria

• stop cycling before finish line due to mechanical or bicycle related errors
• (subjects who stop cycling due to any physical symptoms and health related problem included in analysis)

Trial design

94 participants in 3 patient groups

Group 140kms cycling

Description:

Participants of Tour de Borobudur 2017 140 km cycling touring and willing to participate in the study. Investigator did not give any intervention, just observed the cycling touring event that the subjects participated

Treatment:

Other: 140kms cycling

Group 100kms cycling

Description:

Participants of Tour de Borobudur 2017 100 km cycling touring and willing to participate in the study. Investigator did not give any intervention, just observed the cycling touring event that the subjects participated

Treatment:

Other: 140kms cycling

Group 240kms cycling

Description:

Participants of North Coast 2017 240 km cycling touring and willing to participate in the study. Investigator did not give any intervention, just observed the cycling touring event that the subjects participated

Treatment:

Other: 140kms cycling