Towards Individualized Surgery in Non-focal Congenital Hyperinsulinism (non-focal CHI)

University Medicine Greifswald

Status: Completed

Conditions: Non-focal Congenital Hyperinsulinism

Treatments: Procedure: restrictive pancreatic resection

Study type: Observational

Funder types: Other

Identifiers

NCT02108730

123456

Details and patient eligibility

About

Observational study in patients with non-focal congenital hyperinsulinism showing that restrictive surgery may improve the metabolic situation

Full description

In non-focal congenital hyperinsulinism (CHI) the current doctrine warrants subtotal pancreatic resection in all children who do not respond to medication. However, the rate of diabetes after these extensive resections is very high. In this study investigators show that a less aggressive approach may suffice to wean many children from all medication or to get them manageable medically.

Enrollment: 14 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with non-focal congenital hyperinsulinism

Exclusion criteria

• patients with focal congenital hyperinsulinism

Trial design

14 participants in 1 patient group

non-focal congenital hyperinsulinism

Description:

13 children and one adult with non-focal congenital hyperinsulinism

Treatment:

Procedure: restrictive pancreatic resection