Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors

Rigshospitalet

Status: Completed

Conditions: Germ Cell Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT02303015

DaTeCa01

Details and patient eligibility

About

The purpose of this study is to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.

Full description

Identification of late-effects through questionnaires and linkage to national registries. DNA samples will be gathered through buccal swabs or saliva kits and analysed with whole exome-sequencing.

Enrollment: 430 patients

Sex: Male

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Danish citizen
• Diagnosed with germ cell cancer from 1984 to 2007
• Treated initially at a Danish hospital
• Treated with standard treatment regimens.

Exclusion criteria

• Treated initially at a foreign hospital

Trial design

430 participants in 1 patient group

Danish germ cell cancer patients

Description:

Danish patients with germ cell cancer diagnosed from 1984 to 2007.