Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

Sutter Health

Status: Completed

Conditions: HIV Infections; Toxoplasmosis, Cerebral

Treatments: Drug: Pyrimethamine; Drug: Clindamycin

Study type: Interventional

Funder types: Other

Identifiers

NCT00002064

021A

Details and patient eligibility

About

To compare pyrimethamine and intravenous (IV) clindamycin vs. pyrimethamine and sulfonamides in the treatment of AIDS patients with central nervous system (CNS) Toxoplasma gondii.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Exclusion Criteria

Co-existing Condition:

Patients with the following conditions are excluded:

• Opportunistic infection (Pneumocystis carinii pneumonia (PCP), cryptococcal meningitis) or other conditions (brain abscess) which would make treatment results difficult to interpret due to concurrent infection, disease, or therapy.

Patients with other opportunistic infections or brain diseases are excluded.

Patients with AIDS and cerebral toxoplasmosis.