TPVB, PECSB, ESPB for Postmastectmy Pain (RCT)

Menoufia University

Status: Completed

Conditions: Pain, Postoperative

Treatments: Drug: IV morphine; Procedure: Ultrasound guided block

Study type: Interventional

Funder types: Other

Identifiers

NCT05076773

32900654326

Details and patient eligibility

About

Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries. The hypothesis of the study is that the three groups will give comparative results.

Enrollment: 80 patients

Sex: Female

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. ASA physical status classification class I or II
2. Age group 18 - 60 years of the female gender
3. Patients undergoing breast cancer surgeries

Exclusion criteria

1. Patient refusal
2. History of hypersensitivity to local anesthetics
3. Bleeding disorders or patients receiving anticoagulants
4. Spine or chest wall deformities
5. Pregnancy
6. Local infection at the site of injection.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 4 patient groups, including a placebo group

Control Group (D)

Placebo Comparator group

Description:

Patient will receive opioid only for management of their perioperative pain

Treatment:

Drug: IV morphine

Paravertebral block Group (A)

Active Comparator group

Description:

Will receive thoracic paravertebral block

Treatment:

Procedure: Ultrasound guided block

Drug: IV morphine

Pectoral block Group (B)

Active Comparator group

Description:

Will receive pectoral 1 and 2 block

Treatment:

Procedure: Ultrasound guided block

Drug: IV morphine

Erector spinae block Group (C)

Active Comparator group

Description:

Will receive erector spinae block

Treatment:

Procedure: Ultrasound guided block

Drug: IV morphine