TQLB for Postoperative Pain After Laparoscopic Partial Nephrectomy

Cui Xulei

Status: Completed

Conditions: Nerve Block; Pain Management; Laparoscopic Renal Surgery

Treatments: Procedure: single-injection TQLB(transmuscular quadratus lumborum block); Drug: Morphine given as IPCA(intravenous patient controlled analgesia)

Study type: Interventional

Funder types: Other

Identifiers

NCT03982784

cxl2

Details and patient eligibility

About

This prospective, randomized study,control study aims to compare the analgesic effect,opioids consumption,quality of recovery,length of hospital stay，et al. between single-injection QLB(quadratus lumborum block)+ intravenous patient-controlled analgesia (IPCA) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing laparoscopic partial nephrectomy.

Enrollment: 60 patients

Sex: All

Ages: 17 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-70 yrs
• American Society of Anesthesiologists physical statusⅠ-Ⅲ
• Undergo laparoscopic partial nephrectomy
• Informed consent

Exclusion criteria

• A known allergy to the drugs being used
• Coagulopathy, on anticoagulants
• Analgesics intake, history of substance abuse
• Participating in the investigation of another experimental agent
• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

single-injection TQLB(transmuscular quadratus lumborum block)

Experimental group

Description:

Single-injection of TQLB is given preoperatively + postoperative IPCA(intravenous patient controlled analgesia)

Treatment:

Drug: Morphine given as IPCA(intravenous patient controlled analgesia)

Procedure: single-injection TQLB(transmuscular quadratus lumborum block)

Control

Active Comparator group

Description:

postoperative IPCA is given alone

Treatment:

Drug: Morphine given as IPCA(intravenous patient controlled analgesia)