Tracheal Intubation in COVID-19 Patients

St. Bortolo Hospital

Status: Unknown

Conditions: Tracheal Intubation; COVID-19 Pneumonia

Treatments: Procedure: Endotracheal intubation

Study type: Observational

Funder types: Other

Identifiers

NCT04909476

125/20

Details and patient eligibility

About

The Emergency Endotracheal intubation of a patient who is COVID-19 positive is a high-risk procedure and an additional challenge to an intensivist due to barrier enclosures that have been developed to reduce the risk of COVID-19 transmission to healthcare providers during intubation. Although the incidence of difficult airways is commonly higher in critically ill patients, the evidence of severe hypoxemia without sign of respiratory distress could complicate the scenario.This silent hypoxia often leads to a delayed recognition of the severity of respiratory failure and to a late intubation which is often characterized by a high risk of complications related to the actual airways' management, hemodynamic and cardiac. It has been shown that non-survivors had worse blood gas analyzes than survivors, both before and after intubation. Few studies have reported the implications and adverse events of performing endotracheal intubation for critically ill COVID-19 patients admitted to intensive care units (ICUs).

Enrollment: 143 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Critically ill patient above 18 year old, admitted in the Intensive Care of San Bortolo Hospital, Vicenza, and San Matteo Hospital, Pavia;
• positive specimen for SARS-COV2 PCR;
• tracheal intubation for respiratory distress related to SARS COV2 pneumonia

Exclusion criteria

• negative specimen for SARS-COV2 PCR
• out of hospital intubation
• intubation during cardiac arrest
• intubation in the contest of general anesthesia for surgery

Trial design

143 participants in 1 patient group

Severe COVID pneumonia with ET

Description:

Severe COVID 19 pneumonia undergoing endotracheal intubation

Treatment:

Procedure: Endotracheal intubation