Tracheal Suctioning and Expiratory Pause in Bronchial Hygiene

Hospital de Clinicas de Porto Alegre

Status: Enrolling

Conditions: Mechanical Ventilation

Treatments: Other: 5-Second Expiratory Pause; Other: 10-Second Expiratory Pause

Study type: Interventional

Funder types: Other

Identifiers

NCT05579145

51995621.7.0000.5327

Details and patient eligibility

About

A randomized crossover clinical trial conducted in an Intensive Care Unit of the Hospital de Clinicas de Porto Alegre (HCPA) to compare the efficacy of the two techniques on the amount of aspirated pulmonary secretion and pulmonary mechanics: aspiration of the closed system following an expiratory pause with mechanical ventilator for 5 seconds (5-Second Expiratory Pause) and aspiration of the closed system following an expiratory pause with mechanical ventilator for 10 seconds (10-Second Expiratory Pause).

Full description

After randomization, all patients will be positioned in dorsal decubitus with the head elevated at 30 degrees and will be aspirated once with a closed suction system and with a vacuum of -40cm H2O. Hemodynamic and pulmonary parameters will be collected and recorded. One of the two techniques will be applied, according to randomization, and the outcomes measured. After two hours, hemodynamic and pulmonary parameters will be re-collected, and the second technique will be applied. The outcomes will be measured again.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients in 24 and 72 hours of mechanical ventilation.
• Patients with closed aspiration system.
• Patients hemodynamically stable (mean arterial blood pressure ≥ 60 mmHg and with dose of Noradrenaline ≤ 1μg/kg/minute).

Exclusion criteria

• Undrained pneumothorax and hemothorax.
• Subcutaneous emphysema.
• Patients who refuse to participate in the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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50 participants in 2 patient groups

5-Second Expiratory Pause

Experimental group

Description:

Closed system aspiration following by expiratory pause with mechanical ventilator for 5 seconds.

Treatment:

Other: 5-Second Expiratory Pause

10-Second Expiratory Pause

Experimental group

Description:

Closed system aspiration following by expiratory pause with mechanical ventilator for 10 seconds.

Treatment:

Other: 10-Second Expiratory Pause