Tracking Intervention Effects With Eye Tracking

Yale University

Status: Completed

Conditions: Autism Spectrum Disorder

Treatments: Behavioral: Pivotal Response Treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT02856061

383661 (Other Grant/Funding Number)

1106008625a

Details and patient eligibility

About

This pilot study examines concurrent and predictive relationships between eye tracking and clinical outcomes during a 16-week behavioral intervention (PRT) for children with ASD. Eye tracking will be comprised of both laboratory-based measures (using a commercial eye-tracking system) as well as home-based measures (using tablet-based eye tracking systems). The major goals of this study are both to improve our understanding of the potential role of eye tracking in clinical trials and to advance technologies that may further improve the sensitivity, robustness, accessibility, and ultimate utility of eye tracking methodologies.

Enrollment: 76 patients

Sex: All

Ages: 4 to 7 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Individuals ages 4-7 years diagnosed previously with ASD and meet criteria for ASD when characterized by our research team, English is a language spoken in the family, and Full-scale IQ>50. Participants must also complete laboratory and home-based eye tracking sessions, with success determined by the Principal Investigator.

Exclusion criteria

• Individuals will be excluded from participation based on the presence of

  1. a physical or neurological disorder (e.g., cerebral palsy) which is likely to impact development and learning, as intervention procedures for these individuals may need to be modified beyond the standard approach to address more complex developmental needs,
  2. hearing loss or other severe sensory impairment,
  3. history of significant head trauma or serious brain or psychiatric illness,
  4. parents/caregivers who do not speak fluent English,
  5. parents/caregivers who have previous training in PRT
  6. individuals who must be excluded from eye tracking. These families will be offered the treatment clinically (i.e., fee-based), and they will be given referrals to outside agencies offering the treatment as well.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

76 participants in 3 patient groups

PRT

Other group

Description:

Children with ASD who are currently receiving PRT treatment.

Treatment:

Behavioral: Pivotal Response Treatment

Wait List / Non-Treatment Control

No Intervention group

Description:

Children with ASD who are not currently receiving PRT treatment.

Typically Developing

No Intervention group

Description:

Children without ASD or developmental delay.