Tradeoff Between Spatial and Temporal Resolution

University of North Carolina System

Status: Terminated

Conditions: Deafness

Treatments: Behavioral: Electrode selection/electrode configuration

Study type: Observational

Funder types: Other

Identifiers

NCT03867058

Zhou_R01_study1

Details and patient eligibility

About

In this study, investigators will examine how temporal rate processing might be affected when the width of neural excitation narrows. The manipulation of neural excitation width will be achieved for example by changing electrode configurations or stimulating single versus multiple electrodes simultaneously. Investigators will then measure if the extent to which rate processing is affected by spatially restricted stimulation can predict a subject's overall speech recognition and predict also whether the subject is likely to benefit from a focused electrode configuration. Lastly, investigators will introduce and test a novel current focusing strategy where current focusing is applied in a channel specific manner and quantify if this intervention improves speech recognition. The primary endpoint of the study is speech recognition, and the secondary endpoint is psychophysical sensitivity to stimulation rate change.

Enrollment: 53 patients

Sex: All

Ages: 15+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Native speakers of English
• Cochlear Nucleus cochlear implant users or Advanced Bionics users
• Postlingually deafened
• Has had device experience for at least one year
• Can be child or adult at the time of enrollment

Exclusion criteria

• None

Trial design

53 participants in 1 patient group

Cochlear implant users with Nucleus and AB devices

Description:

Temporal processing acuity will be compared using electrodes or electrode configurations that create broad versus sharp spatial excitation. Speech recognition will be compared in the same group of subjects using electrode-dependent focused versus monopolar stimulation.

Treatment:

Behavioral: Electrode selection/electrode configuration