Traditional Versus ScvO2 Guided Perioperative Fluid Therapy

Haukeland University Hospital

Status and phase: Completed; Phase 4

Conditions: Perioperative Care

Treatments: Procedure: Intravenous fluid

Study type: Interventional

Funder types: Other

Identifiers

NCT00468793

16312

Details and patient eligibility

About

Perioperative goal directed fluid therapy by means of an esophageal doppler has been shown to reduce morbidity and length of stay. In this study patients undergoing elective bowel surgery will be randomised to traditional fluid therapy with crystalloids versus fluid boluses guided by central venous oxygen saturation. The primary outcome will be complications after surgery.

Enrollment: 240 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective bowel surgery,
• Able to give informed consent

Exclusion criteria

• Coagulation defect,
• Renal failure,
• Valvular stenosis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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240 participants in 2 patient groups

2

Active Comparator group

Description:

Fluid therapy guided by blood pressure and urine production

Treatment:

Procedure: Intravenous fluid

1

Experimental group

Description:

ScvO2 guided fluid therapy

Treatment:

Procedure: Intravenous fluid