Training Executive Functions to Facilitate Recovery Following Traumatic Brain Injury

Kessler Foundation

Status: Completed

Conditions: Traumatic Brain Injury; Brain Injuries, Traumatic

Treatments: Behavioral: Control Task; Behavioral: Task Switching Training

Study type: Interventional

Funder types: Other

Identifiers

NCT01993407

R-743-12

Details and patient eligibility

About

The purpose of this research study is to investigate different types of task training to determine if training improves thinking processes following traumatic brain injury.

Enrollment: 28 patients

Sex: All

Ages: 19 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• If you have had a Traumatic Brain Injury (TBI)or no history of neurological disease/damage.
• If you are between the ages of 19 and 65.

Exclusion criteria

For participants with Traumatic Brain Injury:

• If you have a history of prior neurological disorders (e.g., stroke, seizures, or brain tumor).
• If your Brain injury is less than 6 months ago.

For healthy participants:

-If you have a history of prior neurological disorders (e.g., head injury, stroke, seizures, or brain tumor).

For All participants:

• If you have significant psychiatric history (such as schizophrenia or bipolar disorder.)
• If you have a alcohol or drug abuse history.
• If you are currently taking certain types of medications, which the study doctor will review.
• If you do not have a working knowledge of the English Language.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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28 participants in 2 patient groups, including a placebo group

Task Switching Training

Experimental group

Description:

Participants will complete four, one-hour training sessions in which they will practice switching between tasks within an alternating runs task switching paradigm.

Treatment:

Behavioral: Task Switching Training

Pure Task Training

Placebo Comparator group

Description:

Participants will complete four, one-hour training sessions in which they will perform a single task each session, alternating tasks between but not within sessions.

Treatment:

Behavioral: Control Task