Training-induced Cerebral Reorganization in Schizophrenia

University of Konstanz

Status: Completed

Conditions: Schizophrenia

Treatments: Behavioral: Cogpack; Behavioral: Brain Fitness Program

Study type: Interventional

Funder types: Other

Identifiers

NCT00695708

RO 805/14

Details and patient eligibility

About

The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.

Full description

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease.

In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing.

The other training involves a variability of cognitive abilities.

Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.

Enrollment: 60 estimated patients

Sex: All

Ages: Under 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of schizophrenia and disorders with psychotic features
• Intact hearing abilities

Exclusion criteria

• Mental retardation
• Age over 60
• Insufficient German language knowledge

Trial design

60 participants in 3 patient groups

BFT

Experimental group

Description:

20 schizophrenic patients

Treatment:

Behavioral: Brain Fitness Program

CP

Active Comparator group

Description:

19 schizophrenic patients

Treatment:

Behavioral: Cogpack

HCG

No Intervention group

Description:

20 healthy age and sex matched subjects