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Trans-arterial Chemoembolization in Patients With Hepatocellular Carcinoma: A Study of Different Outcomes and Their Predictive Factors

A

Assiut University

Status

Unknown

Conditions

Liver Cancer

Treatments

Procedure: TACE

Study type

Observational

Funder types

Other

Identifiers

NCT04739501
0987654321

Details and patient eligibility

About

Radiological response after trans arterial chemoembolization (TACE) is classified according to Modified Response Evaluation Criteria in Solid Tumors (mRECIST) to: complete response (CR) (disappearance of arterial enhancement), partial response (PR) ( at least a 30% decrease in the sum of diameters of viable enhancement), progressive disease (PD) (an increase of at least 20% in the sum of the diameters of viable enhancement, or appearance of new lesions), and stable disease (any cases that do not qualify for either partial response or progressive disease

Full description

POST-TACE response of treatment for cases of hepatocellular cancer

Enrollment

100 estimated patients

Sex

All

Ages

40+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Clinical history and examination with special stress on symptoms and signs of chronic liver disease with or without evidence of hepatic decompensation e.g. the presence of ascites and with or without evidence of complications e.g. jaundice spider naevi, bleeding varices, ascites, and lower limb edema.

Laboratory findings in the form of raised bilirubin and liver enzymes, impaired coagulation profile, and/or low serum albumin.

Abdominal ultrasonography revealing liver cirrhosis (coarse echopattern, attenuated hepatic veins, irregular outlines, hypertrophy of caudate lobe and/or shrunken liver, presence of focal hepatic) and presence of splenomegaly, ascites, or portal vein thrombosis (PVT).

Exclusion criteria

A patient who had surgical resection or liver transplantation Patients refuse to participate Hepatic focal lesion other than HCC

Trial design

100 participants in 1 patient group

TACE in HCC group 1
Description:
the patient did undergo tace
Treatment:
Procedure: TACE

Trial contacts and locations

1

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Central trial contact

Amany M Ahmed

Data sourced from clinicaltrials.gov

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