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Trans-thoracic Ultrasound VS Invasive Pressure of the Left Atrium (ECHOPOG)

U

University Hospital, Strasbourg, France

Status

Unknown

Conditions

Myocardial Dysfunction

Study type

Observational

Funder types

Other

Identifiers

NCT03012308
6655 - ECHOPOG

Details and patient eligibility

About

As part of cardiac and hemodynamic evaluation of patients, echocardiographic measurements allow indirect evaluation of left ventricular filling pressures (LVFP). These ultrasound parameters, including mitral valve doppler and mitral ring doppler (in particular the E / E 'ratio), are well validated in medical cardiology and in some resuscitation patients. The measurement of filling pressures is an important daily element in the medical management of patients in intensive care, in particular on the hemodynamic and respiratory levels. No studies have evaluated the relevance of these markers in a postoperative context of cardiac surgery. Indeed, the surgery alters the cardiac function, which could modify the values of the echocardiographic parameters and their predictability. Left atrium pressure (LAP) directly reflects LVFP and is measured in cardiac surgical resuscitation by a surgically placed catheter as part of routine institutional care and will serve as gold-standard. To study the clinical significance of these LAP and LVFP values estimated by cardiac ultrasound, we will study their correlation with clinical and ultrasound signs of acute lung edema (ALE).

Enrollment

100 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patient hospitalized in surgical resuscitation for cardiac surgery with heart-lung bypass machine

Exclusion criteria

  • No consent
  • Mitral valve surgery
  • severe MI / severe mitral narrowing.
  • Absence of POG catheter
  • Urgent surgery
  • Heart transplant / mechanical assistance
  • Classics: minors, pregnant women, guardianship / curatorship / safeguarding,

Trial contacts and locations

1

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Central trial contact

Paul-Michel MERTES, MD, PhD; Gharib AJOB, MD

Data sourced from clinicaltrials.gov

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