Transarterial Chemoembolization (TACE) Therapy of Hepatocellular Carcinoma (HCC) With Blocking Tumor Blood Temporarily and Enhancing Perfusion

Naval Military Medical University (Second Military Medical University)

Status and phase

Completed

Phase 2

Phase 1

Conditions

Hepatocellular Carcinoma

Treatments

Procedure: balloon catheter

Study type

Interventional

Funder types

Other

Identifiers

NCT00826384

EHBH-RCT-2008-001

Details and patient eligibility

About

According to radiology imaging, the patients of HCC are divided into two groups(hypovascular tumor group and moderately vascular tumor group). Every group is divided into TACE therapy with balloon catheter subgroup and regular TACE therapy subgroup. Patients take the TACE therapy each 45 days, and have MRI diffusion examine or CT one week before next therapy. All objects are observed until the end event happening or in the group for 6 months.

Enrollment

352 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

sign the written informed consent form provided.
diagnosed clinically as HCC,need to take TACE.

Exclusion criteria

have had an allergic reaction following iodine.
have been in any TACE or radiotherapy or biotherapy within 30 days before the study.
HCC of diffuse type,failure of hepatic function, chronic illness or disease including failure of heart function, uncontrolled high blood pressure, heart disorders, serious infection, uncontrolled diabetes mellitus.