Transbronchial Catheter Aspiration and Transbronchial Needle Aspiration in the Diagnosis of Lung Cancer

Helios Klinik Ambrock

Status: Completed

Conditions: Lung Cancer

Treatments: Procedure: TBCA, TBNA

Study type: Interventional

Funder types: Other

Identifiers

NCT00807391

HELIOS 2090

Details and patient eligibility

About

The aim of this study is prospectively to determine the diagnostic sensitivity of Transbronchial Catheter Aspiration (TBCA) in comparison with Transbronchial Needle Aspiration (TBNA) in the diagnosis of peripheral nodules and masses of the lung.

Full description

The yield of transbronchial forceps biopsy under fluoroscopy in the diagnosis of peripheral lesion of the lung lies between 32 and 57%. Several studies prove an amelioration of success rates by addition of cytological methods such as TBNA, TBCA and bronchial brushing. Furthermore, for TBNA and TBCA a significantly higher yield was reported in comparison with transbronchial forceps biopsy. TBNA and TBCA are routinely used methods, both techniques are safe, the instruments used are certificated.

Enrollment: 48 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• informed consent prior to the procedure
• radiologically peripheral pulmonary lesions between 10 and 60 millimeters in diameter

Exclusion criteria

• endoscopically visible lung carcinoma
• no consent in further diagnostic procedures, when bronchoscopy fails to establish a diagnosis
• haemorrhagic syndrome; grave cardiac disease; oxygen saturation lower than 90 percent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

48 participants in 1 patient group

TBCA/TBNA

Other group

Description:

Under fluoroscopy first transbronchial forceps biopsy is performed, afterwards in random order transbronchial catheter aspiration(TBCA) and transbronchial needle aspiration (TBNA).

Treatment:

Procedure: TBCA, TBNA