ClinicalTrials.Veeva

Menu

Transcranial Direct Current Stimulation in Autistic Spectrum Disorder (TDCSinASD)

F

Federal University of Paraíba

Status

Completed

Conditions

Autistic Disorders Spectrum

Treatments

Device: DLPFC-R (F4) TDCS
Device: sham-tDCS
Device: DLPFC-L (F3) and DLPFC-R (F4) TDCS

Study type

Interventional

Funder types

Other

Identifiers

NCT05311982
Tdcs Autism ufpb

Details and patient eligibility

About

To understand the changes in the resting electroencephalogram (EEG) brain networks of children and adolescents with autistic spectrum disorder (ASD) induced by transcranial direct current stimulation (tDCS), we asked two questions. First: how can tDCS modulate the expression of neural network dynamics? Second: how can tDCS modulate functional connections at specific frequencies? We hypothesized that the tDCS mechanism results in increased cortical frequencies in the areas under the anode, which may reflect an increase in synaptic connectivity, and that this tDCS-related increase changes connection profiles at specific frequencies important for ASD, indicating improvement in symptoms. To verify this improvement, the researchers used the Autism Treatment Evaluation Checklist (ATEC) after an intervention, comparing baseline scores with post-treatment scores.

Enrollment

12 patients

Sex

All

Ages

5 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with ASD reported by a Neuropediatrician; Age group between 5 and 18 years; Mild and moderate clinical symptoms

Exclusion criteria

Patients with severe mental illness; Use of a pacemaker or other metal device on the body; Brain tumor or intracranial infection; Uncooperative parents or caregivers; Epilepsy; structural change in the skull

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Quadruple Blind

12 participants in 3 patient groups

DLPFC-L F3 (Block A)
Active Comparator group
Description:
The study was developed through a triple-blind, crossover, randomized, placebo-controlled clinical trial (dummy tDCS). Participants were randomized into three groups receiving unilateral tDCS in DLPFC-L F3 (Block A)
Treatment:
Device: DLPFC-R (F4) TDCS
Device: DLPFC-L (F3) and DLPFC-R (F4) TDCS
Device: sham-tDCS
tDCS combined in DLPFC-L (F3) and DLPFC-R (F4)
Active Comparator group
Description:
The study was developed through a triple-blind, crossover, randomized, placebo-controlled clinical trial (dummy tDCS). Participants were randomized into three groups receiving unilateral tDCS in tDCS combined in DLPFC-L (F3) and DLPFC-R (F4)
Treatment:
Device: DLPFC-R (F4) TDCS
Device: DLPFC-L (F3) and DLPFC-R (F4) TDCS
Device: sham-tDCS
Sham (Block C)
No Intervention group
Description:
The study was developed through a triple-blind, crossover, randomized, placebo-controlled clinical trial (dummy tDCS). Participants were randomized into three groups receiving unilateral tDCS in tDCS Sham

Trial contacts and locations

2

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems