Transcranial Direct Current Stimulation (tDCS) as a Cognitive Functioning Enhancement Treatment for ADHD Patients Compared to Healthy Controls

Hebrew University of Jerusalem

Status: Completed

Conditions: Transcranial Direct Current Stimulation

Treatments: Device: Sham; Device: Transcranial Direct Current Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT04697316

tDCS-ADHD

Details and patient eligibility

About

This study will examine the possible effects of tDCS (Transcranial Direct Current Stimulation) treatment to the left DLPFC on cognitive functions which were found to be deficient amongst ADHD patients. The study will include 100 subjects, 50 of whom diagnosed with ADHD. Subjects will complete the ASRS questionnaire to measure ADHD symptoms severity. Next, subjects will complete a series of cognitive tasks, after which they will receive either tDCS treatment or a sham treatment. Finally, subjects will repeat the cognitive tasks. Later that day, a telephonic follow up will take place. ADHD symptoms will be assessed again the next day.

Enrollment: 63 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Participation criteria for healthy participants

1. Right hand dominance.
2. No psychiatric nor neural diagnosis.
3. Participants must be able to comprehend the study's procedure and sign an informed consent.

Participation criteria for ADHD diagnosed participants

1. ADHD diagnosis (according to DSM V).

2. Right hand dominance.

3. Participants must be able to comprehend the study's procedure and sign an informed consent.

4. Participants who regularly use Methylphenidate will be required to avoid the medication for 24 hours prior to study and 12 hours post study.

Exclusion Criteria:

• a. Other psychiatric diagnoses (additional to ADHD). b. Drug use (excluding Methylphenidate). c. Neurological disorders. d. Pacemaker, Insulin pump

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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63 participants in 4 patient groups

ADHD tDCS

Experimental group

Treatment:

Device: Transcranial Direct Current Stimulation

ADHD Sham

Sham Comparator group

Treatment:

Device: Sham

Healthy control tDCS

Experimental group

Treatment:

Device: Transcranial Direct Current Stimulation

Healthy control Sham

Sham Comparator group

Treatment:

Device: Sham