Transcranial Direct Current Stimulation to Enhance Cognition in Mild Cognitive Impairment

The University of New South Wales

Status and phase: Completed; Phase 2; Phase 1

Conditions: Mild Cognitive Impairment

Treatments: Device: Transcranial direct current stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT01653431

HC12381

Details and patient eligibility

About

The study will examine whether the effects of computerized brain training are enhanced when training is combined with mild brain stimulation in patients with mild cognitive impairment. We hypothesize that this combination will produce greater improvements in cognitive functioning than computerized brain training alone.

Enrollment: 68 patients

Sex: All

Ages: 60 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Aged 60 - 85 years.
• Meet diagnostic criteria for amnestic mild cognitive impairment.

Exclusion criteria

• Inability to provide informed consent.
• Concurrent medication likely to affect mental performance.
• Current substance use or dependence in last 3 months.
• Current active psychiatric or neurological condition

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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68 participants in 2 patient groups

Transcranial direct current stimulation

Experimental group

Description:

Transcranial direct current stimulation combined with cognitive training

Treatment:

Device: Transcranial direct current stimulation

Sham transcranial direct current stimulation

Sham Comparator group

Description:

Sham transcranial direct current stimulation combined with cognitive training

Treatment:

Device: Transcranial direct current stimulation