Transcranial Direct Current Stimulation - Tobacco Use Disorder

Central Institute of Mental Health, Mannheim

Status

Completed

Conditions

Tobacco Use Disorder

Treatments

Device: Sham tDCS

Device: tDCS

Study type

Interventional

Funder types

Other

Identifiers

NCT03691805

tDCS-TUD

Details and patient eligibility

About

This study aims to detect how transcranial direct current stimulation (tDCS) affects smokers' inhibitory control, craving and consumption of tobacco goods.

Full description

Participating smokers are to receive anodal transcranial direct current stimulation of the right dorsolateral prefrontal cortex (rDLPFC) for 20 minutes on five consecutive days. Neuropsychological tests on inhibitory control and interviews on smoking habits and craving will be applied before and after the first stimulation as well as after the fifth stimulation.

After a follow-up period of three days, smoking behaviour will be assessed in a telephone interview.

Changes in inhibitory control and smoking behaviour will be compared between an active and a sham stimulation group.This way the effects of transcranial direct current stimulation on tobacco use disorder are to be clarified.

Enrollment

44 patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

tobacco use disorder
normal or correctable eyesight
sufficient ability to communicate with the investigators, to answer questions in oral and written form
fully informed consent
written informed consent

Exclusion criteria

withdrawal of the declaration of consent
exclusion criteria for tDCS (metal implants in the head, acute eczema, known epilepsy)
severe internal, neurological or psychiatric comorbidity
pharmacotherapy with psychoactive substances within the last 14 days
axis-I disorder according to ICD-10 and DSM 5 (except tobacco use disorder)
positive urin drug screening (cannabis, amphetamine, opiates, benzodiazepines, cocaine)
pregnancy