Transcranial Doppler and Quantitative Pupillometry as Neurological Prognostic Factors in Brain Damaged Patients Admitted to Intensive Care Unit

Centre Hospitalier Universitaire de Saint Etienne

Status: Completed

Conditions: Brain Damage

Treatments: Device: Pupillometry.; Device: Transcranial Doppler

Study type: Observational

Funder types: Other

Identifiers

NCT04846738

IRBN282021/CHUSTE

Details and patient eligibility

About

Transcranial Doppler is performed daily in Intensive Care Unit in brain damaged patients. For a few years now, the measurement of the photomotor reflex by quantitative Pupillometry has been routinely performed in Intensive Care Units. The objective of this work is to see if Transcranial Doppler recorded parameters and Pupillary parameters are correlated to the neurological prognosis evaluated at 9 months by the Modified Rankin Score (mRS) and the Glasgow Outcome Scale Extended (GOS-E).

Enrollment: 73 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All brain damaged patients (stroke or head trauma)
• Admitted to Intensive Care Unit since December 1, 2020

Exclusion criteria

• Refusal by the patient or his/her legal representative.
• Benefiting from legal protection

Trial design

73 participants in 1 patient group

brain damaged patients

Description:

All major brain damaged patients (stroke or head trauma) admitted to reanimation will be included. In the usual practice, they have a Transcranial Doppler and the measurement of the photomotor reflex by quantitative Pupillometry. It is planned to collect the simultaneous values of the different parameters during 2,000 measurements. The data will be collected retrospectively from 01/12/2020, and prospectively from 01/04/2021.

Treatment:

Device: Transcranial Doppler

Device: Pupillometry.