Transcranial Doppler During Liver Transplantation

Mansoura University

Status: Unknown

Conditions: Liver Transplantation; Complication, Postoperative; Ultrasonography, Doppler, Transcranial; Neurologic Deficits

Treatments: Diagnostic Test: Transcranial Doppler

Study type: Interventional

Funder types: Other

Identifiers

NCT05144451

MD.21.09.535

Details and patient eligibility

About

This is a prospective study that would investigate the transcranial doppler (TCD) changes during the living donor liver transplantation and the association between the TCD changes and the post-transplant neurological complications.

Full description

Objectives:

Participants & Setting:

Intervention & Measurements:

Sample size:

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients scheduled for living donor liver transplantation for whatever the indication at Gastrointestinal surgery center (GISC)

Exclusion criteria

• Patients with coexisting neuropsychiatric or cerebrovascular disorders or those who have a history of head trauma or brain surgery

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

TCD arm

Experimental group

Description:

All patients will be evaluated with TCD for prediction of the post-transplant neurological complications

Treatment:

Diagnostic Test: Transcranial Doppler