Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements (DOPPLER)

Centre Hospitalier Universitaire de la Réunion

Status: Enrolling

Conditions: Neurological Complication

Treatments: Other: Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)

Study type: Observational

Funder types: Other

Identifiers

NCT05843214

2021/CHU/04

Details and patient eligibility

About

Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring with the aim, among others, of detecting episodes of intracranial hypertension, each method allowing the study of one of the different pathophysiological mechanisms of its impact.

However, at present there is no data in the literature on the value of these non-invasive neuromonitoring tools in the management of patients undergoing controlled intracranial surgery.

The study aims to help the early detection of postoperative neurological deterioration.

Enrollment: 230 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Regulated intracranial surgery: scheduled > 48 hours
• French-speaking patient
• No opposition from the patient or a relative when the patient is unable to consent

Exclusion criteria

• Chronic subdural haematoma
• Isolated cerebral endovascular procedure
• Stereotactic biopsy
• Scheduled ventriculoperitoneal shunt or isolated ventriculocisternostomy
• Specific non-inclusion criteria for quantitative pupillometry: known pupillary abnormalities, glaucoma, cataract surgery and any ocular surgery.