Transcranial Magnetic Stimulation for Borderline Personality Disorder (SiMaT-B)

Toulouse University Hospital

Status: Completed

Conditions: Borderline Personality Disorder

Treatments: Procedure: sham rTMS; Procedure: repetitive Transcranial Stimulation Magnetic (rTMS)

Study type: Interventional

Funder types: Other

Identifiers

NCT01076933

AOL 2008

08 153 02

Details and patient eligibility

About

Primary purpose : to assess the effect on neuropsychological tasks related to planning of 10 daily sessions of right dorsolateral prefrontal cortex with High-frequency repetitive transcranial magnetic stimulation (rTMS) on borderline personality disorder (BPD) patients.

Hypothesis : BPD patients receiving 10 sessions of rTMS will have greater improvement in the average number of move to achieve tasks of the Tower of London, than those receiving sham rTMS.

Enrollment: 13 patients

Sex: All

Ages: 20 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 20 to 45 years old
• Borderline Personality Disorder (Diagnostic Interview for Borderline Personality Disorder > 8)
• psychiatric follow-up
• righthander
• informed consent
• affiliated to medical insurance

Exclusion criteria

• bipolar disorder
• substance use disorder
• Major Depressive Disorder or Stress Post Traumatic Disorder
• history of epilepsy
• neurosurgery
• cardiac pacemaker
• lefthander
• involuntary admission
• participation in an other research
• legal guardianship
• poor mastery of french.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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13 participants in 2 patient groups

rTMS

Experimental group

Description:

rTMS sessions

Treatment:

Procedure: repetitive Transcranial Stimulation Magnetic (rTMS)

control

Sham Comparator group

Description:

sham rTMS (control)

Treatment:

Procedure: sham rTMS