Transcranial Magnetic Stimulation (TMS) in Binge Eating Disorder (BED) (TMS&BED)

Universidad Autonoma de Queretaro

Status: Completed

Conditions: Binge-Eating Disorder

Treatments: Device: MagVenture MagPro R30

Study type: Interventional

Funder types: Other

Identifiers

NCT03540641

9320

Details and patient eligibility

About

This study evaluates de efficacy of 5Hz repetitive Transcranial Magnetic Stimulation (rTMS) applied on the left dorsolateral prefrontal cortex in patients with binge eating disorder.

Full description

Binge Eating Disorder (BED) affects a significant percentage of de national population (1.4%) in a portio 2-1 in woman compared with men, the repetitive Transcranial Magnetic Stimulation (rTMS) is a neuromodulation technique, which allows us to induce brain electrical activity by plating magnetic fields and it has been proven that at 10Hz it has an effect of improvement in the craving of food.

Enrollment: 30 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Subjects of both sexes.
2. Subjects from 18 to 45 years of age.
3. Subjects with diagnosis of binge eating disorder.
4. Subjects without changes in pharmacological treatment in the last 30 days.
5. Subjects who agree to sign the informed consent letter.

Exclusion criteria

1.Subjects with a history of traumatic brain injury with loss of consciousness. 2.Subjects with intracranial metallic objects or metal plates in the skull.

3.Subjects who suffer chronic diseases not controlled at the time of entering the study (for example: hypertension, diabetes, rheumatic diseases).

4.Patients with psychotic symptoms, bipolar affective disorders and substance dependence.

5.Subjects with alterations in electroencephalogram (epileptiform activity). 6.Patients with any type of chronic or neurological medical disease not controlled.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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30 participants in 4 patient groups

1500 pulses

Active Comparator group

Description:

This group will receive 1500 pulses of transcranial magnetic stimulation at 5Hz over the left dorsolateral prefrontal cortex, until completing 15 sessions

Treatment:

Device: MagVenture MagPro R30

1500 pulses sham

Sham Comparator group

Description:

this group will receive the sham modality of the protocol of 1500 pulses at 5Hz of transcranial magnetic stimulation during 15 sessions.

Treatment:

Device: MagVenture MagPro R30

5000 pulses

Active Comparator group

Description:

This group will receive 5000 pulses of transcranial magnetic stimulation at 5Hz over the left dorsolateral prefrontal cortex, until completing 15 sessions.

Treatment:

Device: MagVenture MagPro R30

5000 pulses sham

Sham Comparator group

Description:

this group will receive the sham modality of the protocol of 5000 pulses at 5Hz of transcranial magnetic stimulation during 15 sessions.

Treatment:

Device: MagVenture MagPro R30