Transcultural Multidisciplinary Evaluation of Patients With Hemophili (ibHEro)

Universidad Católica San Antonio de Murcia

Status: Unknown

Conditions: Patients With Haemophilia

Study type: Observational

Funder types: Other

Identifiers

NCT02199639

ibHEro

Details and patient eligibility

About

Multidisciplinary evaluation of patients with hemophilia Spain, El Salvador and Bolivia. It aims to analyze and evaluate the skeletal muscle of patients affected with hemophilia Spain, El Salvador and Bolivia; describe deficit mobility and muscular strength, depending on the degree of injury, age, presence of inhibitors and the development of physical activity; identify the relationship between the functional deficit by clinical assessment performed with the use of validated measurement scales, the assessment of the degree of injury to specific scales of hemophilia; detect biomechanical alterations of the lower limbs and their impact on gait in patients with hemophilia; and evaluate the factors that influence the perception of illness and quality of life of patients with hemophilia.

Full description

Descriptive study of joint involvement in patients with hemophilia Spain, El Salvador and Bolivia.

Descriptive study of abnormal joint mobility and muscle strength as a result of acute conditions or the development of chronic articular sequelae.

Descriptive study of biomechanical changes in lower limb joints and their impact on gait in patients with hemophilia.

Descriptive study of the overall articular involvement (crepitus, pain, biomechanical and functional changes) in patients with hemophilia.

Descriptive study of the relationship between skeletal muscle pathology in patients with hemophilia and their perception of it, and their quality of life.

Enrollment: 100 estimated patients

Sex: Male

Ages: 6 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with hemophilia A and B.
• Patients of all ages (pediatric, adolescents, youth and adults).
• With or without joint involvement clinically diagnosed, and with or without a previous history of hemarthrosis joint load legs.
• Patients with or without inhibitors.

Exclusion criteria

• Patients without prior ambulation capacity.
• Patients diagnosed with other congenital coagulopathy (von Willebrand disease, etc..).
• Patients with neurological or cognitive impairments that prevent understanding the questionnaires and physical tests.

Trial design

100 participants in 3 patient groups

Spain

Description:

Group of patients with hemophilia recruited in the Region of Murcia (Spain) and evaluated in the Universidad Católica San Antonio between June and July 2014.

El Salvador

Description:

Group of patients with hemophilia recruited in the city of San Salvador (El Salvador) and evaluated in the Hospital Nacional Rosales and the Hospital Nacional de niños "Benjamín Bloom" from San Salvador in April 2014.

Bolivia

Description:

Group of patients with hemophilia recruited in the city of Santa Cruz (Bolivia) and evaluated at the Hospital Nacional de niños in Santa Cruz August 2014.