Transcutaneous Electrical Acupoint Stimulation on Postoperative Dizziness in Hemifacial Spasm Patients

Peking University

Status: Completed

Conditions: Dizziness; Hemifacial Spasm; Transcutaneous Electrical Acupoint Stimulation

Treatments: Device: HANS 100B stimulator (4 conductors, 8 electrodes; Jisheng Co., Nanjing, China)

Study type: Interventional

Funder types: Other

Identifiers

NCT04621578

2020PHB232-01

Details and patient eligibility

About

To observe the prevention and treatment effect of transcutaneous electrical acupoint stimulation (TEAS) on postoperative dizziness in patients with hemifacial spasm undergoing microvascular decompression surgery, and its possible mechanisms.

Full description

Hemifacial spasm (HFS) is mainly caused by vascular compression on the roots of the VII cranial nerves from the brain stem. Microvascular decompression (MVD) is the exact surgical method for the treatment of HFS, but the incidence of dizziness and postoperative nausea and vomiting (PONV) after MVD is extremely high. Despite the use of dual antiemetic therapy during the operation, the incidence of PONV within 24 hours after MVD is still as high as 66.7%. Medication alone has limited effects on dizziness and PONV treatment after MVD. Meta-analysis shows that transcutaneous electrical acupoint stimulation (TEAS) is associated with the reduction of post-emetic remedies and the incidence of dizziness after general anesthesia, and it can be integrated into the multi-modal therapy of PONV. Therefore, the purpose of our study is to observe the prevention and treatment effect of TEAS on postoperative dizziness in patients with hemifacial spasm undergoing microvascular decompression surgery, and explore its possible mechanisms.

Enrollment: 86 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologists (ASA) physical status: I-III
• Body mass index (BMI): 18-30
• Diagnosed of hemifacial spasm
• Undergoing microvascular decompression surgery

Exclusion criteria

• Pregnant or lactating women
• Poorly controlled hypertension or poorly controlled diabetes, severe cardiovascular and cerebrovascular diseases and mental illness
• Cardiac pacemakers
• Scars on bilateral Neiguan acupoints or on the mastoid area
• Upper limb nerve injury
• Raynaud's syndrome
• Motion sickness or PONV history
• Eye diseases (glaucoma, cataracts, eye trauma, etc.) or previous eye surgery
• Participate in other clinical trials

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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86 participants in 2 patient groups

Transcutaneous electrical acupoint stimulation arm

Experimental group

Description:

Patients will be given TEAS treatment at the maximum tolerable intensity at a frequency of 2 Hertz (Hz) after surgery in postanesthesia care unit (PACU), and after returning to the ward.

Treatment:

Device: HANS 100B stimulator (4 conductors, 8 electrodes; Jisheng Co., Nanjing, China)

Sham stimulation arm

Sham Comparator group

Description:

Patients will use the same device, same stimulation site, and be treated at the same time points, but the lead of the device was damaged. Therefore, although the patients can see the stimulator running, there is actually no current passing through.

Treatment:

Device: HANS 100B stimulator (4 conductors, 8 electrodes; Jisheng Co., Nanjing, China)