Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hepatic and Renal Dysfunction After Pneumoperitoneum (TRIP)

Zhihong LU

Status: Completed

Conditions: Hepatic Dysfunction Transient; Renal Function Disorder

Treatments: Other: TEAS pretreatment; Other: TEAS treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT02013596

XJH-A-2013-08-2

Details and patient eligibility

About

The purpose of this study is to compare the effect of TEAS pretreatment and treatment on hepatic and renal dysfunction induced by pneumoperitoneum in patients undergoing laparoscopic surgeries.

Full description

Patients were randomly assigned to three groups, control group and two intervention groups, receiving TEAS before and after general anesthesia induction respectively. TEAS was given through electrodes attached to acupoints. The time for TEAS was 30min. Venous blood samples were collected before and 20min after pneumoperitoneum. Hepatic and renal function index including AST, ALT, ALP, BUN, Cr were measured.

Enrollment: 168 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>18yrs,<60yrs；
• ASA 1-2；
• Scheduled for laparoscopic surgery under general anesthesia；
• Informed consented

Exclusion criteria

• Patients with hepatic or renal dysfunction；
• Patients with severe hypertension or cardiac dysfunction；
• Patients with severe pulmonary disease；
• Patients with hemoglobin<100g/L

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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168 participants in 3 patient groups

Control

No Intervention group

Description:

Patients were given no TEAS

TEAS Pretreatment

Experimental group

Description:

Patients were given 30min of TEAS before pneumoperitoneum

Treatment:

Other: TEAS pretreatment

TEAS Treatment

Experimental group

Description:

Patients were given 30min of TEAS during pneumoperitoneum

Treatment:

Other: TEAS treatment