Transcutaneous Posterior Tibial Nerve Electrostimulation With Low Dose Trospium Chloride in OAB in Females

Alexandria University

Status

Completed

Conditions

Overactive Bladder

Treatments

Device: TPTNS

Combination Product: TPTNS+Drug

Study type

Interventional

Funder types

Other

Identifiers

NCT03104101

Alexandria University

Details and patient eligibility

About

This study was done to verify whether the combination of transcutaneous posterior tibial nerve stimulation (TPTNS) with low dose trospium chloride in the treatment of females with overactive bladder (OAB) would be more effective than TPTNS alone after failure of behavioral therapy.

Full description

The investigators randomized 30 women with OAB, in two groups: G I (15 patients) received 30 minutes TPTNS, three times a week; GII (15 patients) received TPTNS plus Low dose trospium chloride (20 mg once daily); all for 8 weeks. Patients were evaluated using Overactive Bladder Symptom Score questionnaire (OABSS), Incontinence Impact Questionnaire-short form 7 (IIQ-7), 3 day voiding diary and urodynamics at weeks 0 and 8.

Enrollment

30 patients

Sex

Female

Ages

20 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Thirty adult female patients having OAB symptoms (wet type) and proved to have detrusor overactivity by urodynamics

Exclusion criteria

Patients having urinary tract infection or bladder outlet obstruction.
Patients having neurological diseases.
Patients having gynecological problems as genital infection, pelvic organ prolapse or genital tumors.
Patients with electronic implants such as heart pacemakers.
During pregnancy
Patients subject to seizures