Transdermal Testosterone for Poor Responder Patients Undergoing Controlled Ovarian Stimulation Prior to IVF

Wolfson Medical Center (WMC)

Status and phase: Unknown; Phase 4

Conditions: Infertility, Female

Treatments: Drug: Testosterone gel

Study type: Interventional

Funder types: Other

Identifiers

NCT03078569

wolfson testosterone 1

Details and patient eligibility

About

This study evaluates the efficacy of pre- IVF treatment with transdermal testosterone to enhance ovarian response in poor responders.

a randomized controlled trial with two groups, treatment group with transdermal testosterone before IVF treatment and a control group with no treatment.

Full description

One of the major challenges of Assisted reproduction technology is treating women with low ovarian response,those women achieve very poor pregnancy rate with IVF.

in recent years there is a focus

Enrollment: 30 estimated patients

Sex: Female

Ages: 30 to 42 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• infertility patients undergoing ART regular menses normal function of thyroid, liver and kidney normal BMI (19.3-28.9) without use of any fertility drugs in the previous two months

Exclusion criteria

• patients with recurrent implantations failure (3 cycles and more) previous ovarian surgery uncontrolled medical illness severe endometriosis (stage 3-4) contraindication for testosterone use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 2 patient groups

testosterone gel

Experimental group

Description:

testosterone gel treatment group

Treatment:

Drug: Testosterone gel

Control group

No Intervention group

Description:

without testosterone treatment