Transit Time Flow Measurement in Coronary Surgery (COLLATERAL)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Not yet enrolling

Conditions: Coronary Bypass Graft Stenosis; Coronary Artery Disease; Coronary Stenosis

Study type: Observational

Funder types: Other

Identifiers

NCT06471062

6646

Details and patient eligibility

About

Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.

To date, many studies have deeply studied the predictive role on the graft outcomes of the various flowmetry-derived parameters. One of the least investigated aspects, however, is the mutual influence that two newly realized grafts can have. This possibility would be related to the presence of a more or less developed collateral circulation between the bypassed territories.

The purpose of this study is to assess whether a graft for a territory different than that provided by the left anterior descending artery (LAD) may affect the functionality (measured through flowmetry) of the left internal mammary artery - LAD graft.

Enrollment: 135 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age > 18 years;
• informed consent acquired and registered;
• patients who undergo coronary artery bypass grafting (with or without cardiopulmonary bypass);
• patients with stable angina, unstable angina or acute coronary syndrome without elevation of the ST tract (NSTEMI)

Exclusion criteria

• patients unable to give informed consent;
• patients undergoing emergency surgery;
• patients in unstable haemodynamic conditions or in need of pharmacological or mechanical support;
• patients undergoing combined surgery;
• patients undergoing single aortocoronary bypass surgery

Trial design