Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Completed

Conditions: Laparoscopic Adrenalectomy; Nerve Block; Pain Management

Treatments: Procedure: Placebo Control; Procedure: single-injection QLB(quadratus lumborum block)

Study type: Interventional

Funder types: Other

Identifiers

NCT03942237

cuixulei8

Details and patient eligibility

About

This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Enrollment: 72 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-70 yrs
• American Society of Anesthesiologists physical statusⅠ-Ⅲ
• Undergo laparoscopic adrenalectomy
• Informed consent

Exclusion criteria

• a known allergy to the medications being used for anesthesia
• coagulopathy or on anticoagulants
• chronic opioid therapy or history of substance abuse
• participating in another RCT
• inability to properly describe postoperative pain to investigators (e.g., language barrier, neuropsychiatric disorder).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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72 participants in 2 patient groups, including a placebo group

single-injection QLB (quadratus lumborum block)

Experimental group

Description:

Single-injection of QLB with local anesthetic is given preoperatively

Treatment:

Procedure: single-injection QLB(quadratus lumborum block)

Placebo control

Placebo Comparator group

Description:

Single-injection of QLB with NS is given preoperatively

Treatment:

Procedure: Placebo Control