ClinicalTrials.Veeva

Menu

Transperineal Laser Ablation Treatment (TPLA) for Prostate Cancer (PCa) Registry (TPLAforPCa)

A

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Status

Enrolling

Conditions

Prostate Cancer

Treatments

Procedure: Transperineal Laser Ablation of Prostate Cancer

Study type

Observational

Funder types

Other

Identifiers

NCT05163197
W21_458

Details and patient eligibility

About

Rationale: Transperineal laser ablation (TPLA) treatment for prostate cancer (PCa) is a minimal invasive focal therapy technique studied worldwide to determine its efficacy. In pilot studies it has shown to be a safe and feasible technique and it has potential to preserve continence and potency over current standard radical therapies. However, (long-term) treatment outcomes of TPLA for PCa remain largely unknown. The aim of this international retrospective registry is to collect and combine data on patients treated TPLA for PCa in order to provide data on safety, feasibility, functional and oncological outcomes.

Objective: To assess safety and feasibility of TPLA for PCa, to assess functional and oncological outcomes of TPLA for PCa and to determine baseline patient characteristics in a multicentre cohort.

Study design: This is an international, retrospective observational registry in which data is recorded of patients who have been treated with TPLA for PCa.

Study population: Male patients treated with TPLA for PCa. Main study parameters/endpoints: The primary endpoint of this registry is oncological outcomes of TPLA for PCa. Secondary endpoints are safety, feasibility and functional outcomes of TPLA for PCa.

Enrollment

200 estimated patients

Sex

Male

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Male, histological-confirmed disease of localized prostate cancer, TPLA treatment for PCa is performed

Exclusion criteria

  • Age < 18 years

Trial contacts and locations

1

Loading...

Central trial contact

J. R. Oddens, MD, PhD; L. A. van Riel, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems