Transpharyngeal Doppler Sonography for Cerebral Perfusion Monitoring (TaPaS)

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Cerebral Perfusion

Treatments: Diagnostic Test: Conventional colour-coded Duplex sonography (CDS); Diagnostic Test: Transpharyngeal Doppler sonography (TPS)

Study type: Interventional

Funder types: Other

Identifiers

NCT03494413

2018-00566

Details and patient eligibility

About

This prospective interventional study investigates transpharyngeal sonography (TPS) as an additional neuromonitoring strategy to assess cerebral perfusion during cardiovascular surgery. In the first part of the study the investigators will investigate the feasibility of TPS for visualization of aortic arch branches including the innominate and the carotid arteries in patients undergoing cardiac surgery with cardiopulmonary bypass. In the second part the investigators plan to adopt the investigators previous experiences on TPS to a selected population of patients undergoing ascending aortic and/or arch repair in hypothermic circulatory arrest (HCA).

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cardiovascular Surgery
• Age > 18 yrs
• Informed Consent

Exclusion criteria

• Contraindication for TPS
• Carotid artery stenosis

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

---

30 participants in 2 patient groups

20 patients (1-20) validation arm

Experimental group

Description:

Accuracy of cerebral flow measurement between TPS and CDS in 20 patients undergoing cardiovascular surgery with cardiopulmonary bypass

Treatment:

Diagnostic Test: Conventional colour-coded Duplex sonography (CDS)

Diagnostic Test: Transpharyngeal Doppler sonography (TPS)

20 patients (21-40) HCA arm

Experimental group

Description:

Assessment and comparison of TPS and CDS in hypothermic circulatory arrest (HCA) during cardiovascular surgery

Treatment:

Diagnostic Test: Conventional colour-coded Duplex sonography (CDS)

Diagnostic Test: Transpharyngeal Doppler sonography (TPS)