Transplant and Addiction Project (TAP) - 1

St. Luke's-Roosevelt Hospital Center

Status and phase

Completed

Phase 2

Phase 1

Conditions

Substance-Related Disorders

End Stage Renal Disease

End Stage Liver Disease

Treatments

Other: TAU

Behavioral: TAP

Study type

Interventional

Funder types

Other

Identifiers

NCT00249652

NIDA-15772-1

R01-15772-1

Details and patient eligibility

About

The purpose of this study is to test a novel distance-based (telephone) intervention to help transplant candidates with current or recent substance abuse to stay "clean and sober" both prior and following transplant surgery.

Full description

Participants who need a liver or renal transplant and who are ineligible due to current or recent (past 6 months) alcohol and/or other drug abuse are being recruited from the transplant programs at St. Luke's-Roosevelt Hospital Center (renal), Columbia Presbyterian Hospital (renal/liver) and Virginia Commonwealth University Medical Center (liver). Baseline and follow-up computer-assisted assessments and structured clinical interviews along with collection of biological samples (urine, hair) will occur in the transplant clinics; however, phone counseling sessions originate at St. Luke's. Participants are randomly assigned to one of two treatments: (1) usual care (no phone counseling) or (2) usual care + counseling. The telephone counseling sessions are designed to help participants become motivated to remain abstinent and improve other health behaviors such as sleep or stress management.

Enrollment

41 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

End stage liver or renal disease
Having used drugs or alcohol during the past 6 months
Turned down for transplant due to current or recent substance use
Access to telephone

Exclusion criteria

Psychotic or other unstable serious psychiatric disorders that preclude full, active participation
Moderate to severe hepatic encephalopathy
Non-English speaking