Transplantation for Patients With Chronic Lymphocytic Leukemia

Stanford University

Status: Completed

Conditions: Leukemia, Lymphocytic, Chronic

Treatments: Procedure: ablative allogeneic hematopoietic cell transplant; Procedure: high dose chemotherapy then autologous hematopoietic cell transplant

Study type: Interventional

Funder types: Other

Identifiers

NCT00186303

BMT88

NCT00186303

77066

Details and patient eligibility

About

To evaluate the role of high dose therapy and autologous or allogeneic hematopoietic cell transplantation for the treatment of chronic lymphocytic leukemia.

Full description

To determine effectiveness of allogeneic transplantation in eradicating chronic lymphocytic leukemia.

Enrollment: 28 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:- adequate organ function

• normal bone marrow cytogenetics Exclusion Criteria:- active CNS disease
• For autologous patients more than 30% bone marrow involvement

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)