Transpulmonary Pressure and Airway Pressure Release Ventilation (APRV).

Public Assistance-Hospitals of Marseille (AP-HM)

Status: Completed

Conditions: Patient Mechanically Ventilated With APRV Mode

Treatments: Other: evaluate the variations of transpulmonary pressure during the use of APRV by clinicians.

Study type: Interventional

Funder types: Other

Identifiers

NCT02866513

2015-19

Details and patient eligibility

About

Mechanical ventilation can induce pulmonary lesions called ventilator induced lung injury (VILI). High levels of Transpulmonary pressure is one of the most important mechanism of VILI during the use of mechanical ventilation. The use of bilevel pressure ventilator modes like APRV could generate high levels of transpulmonary pressure.

The aim of this study is to evaluate the variations of transpulmonary pressure during the use of APRV by clinicians

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult
• Patient mechanically ventilated for more than 48 H for acute respiratory failure
• Decision to use of the APRV mode by clinicians in charge of the patient

Exclusion criteria

• Contraindication for the use of a nasogastric tube

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

20 participants in 1 patient group

Patient mechanically ventilated with APRV mode

Other group

Treatment:

Other: evaluate the variations of transpulmonary pressure during the use of APRV by clinicians.