TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair

Assiut University

Status: Enrolling

Conditions: Inguinal Hernia Repair; Inguinal Hernia

Treatments: Procedure: trans rectus sheath extra-peritoneal procedure (TREPP)

Study type: Interventional

Funder types: Other

Identifiers

NCT07618884

RF-1-6-2025

Details and patient eligibility

About

Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role.

The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.

Full description

This is a prospective cohort study

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults with primary unilateral or bilateral inguinal hernia

Exclusion criteria

• Strangulated hernias.
• Severe comorbidities precluding surgery ((ASA Class IV,V)

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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30 participants in 1 patient group

TREPP group

Experimental group

Description:

Patients undergoing TransREctus Sheath PrePeritoneal Procedure (TREPP) for inguinal hernia repair

Treatment:

Procedure: trans rectus sheath extra-peritoneal procedure (TREPP)